{"id":11555,"date":"2024-06-12T13:22:18","date_gmt":"2024-06-12T06:22:18","guid":{"rendered":"https:\/\/www.research.chula.ac.th\/center-of-expertise-in-cross-disciplinary-research-in-diseases-related-to-inflammation-and-immune-system-diseases\/"},"modified":"2024-06-15T17:08:08","modified_gmt":"2024-06-15T10:08:08","slug":"ce-translational-research-in-inflammation-and-immunology","status":"publish","type":"page","link":"https:\/\/www.research.chula.ac.th\/en\/ce-translational-research-in-inflammation-and-immunology\/","title":{"rendered":"Center of Excellence in Translational Research in Inflammation and Immunology"},"content":{"rendered":"\t\t
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Center of Excellence in Translational Research in Inflammation and Immunology, The translation of the basic research into clinical practice; bench to bedside translation.<\/p>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Research & Innovation Focus \u200b<\/h2>\t\t<\/div>\n\t\t\n\t\t\t\t
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Health and Well-Being + Health<\/h6>\t\t<\/div>\n\t\t\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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Health and Well-Being + BCG<\/h6>\t\t<\/div>\n\t\t\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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Health and Well-Being + Industry 4.0<\/h6>\t\t<\/div>\n\t\t\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Strategic Objectives<\/h3>\t\t<\/div>\n\t\t\n\t\t\t\t
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  1. Translation of basic knowledge in the control of inflammation and immune responses into the clinical situation (clinical practice or health advice)<\/li>
  2. Discovery of the new knowledge for the control of inflammation and immune responses using translational research<\/li><\/ol>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Target in 3 Years<\/h3>\t\t<\/div>\n\t\t\n\t\t\t\t
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    1. The innovation<\/li><\/ol>
        • Probiotics-derived from Thai population (Lacticaseibacillus rhamnosus L34) is developing with Greater Pharma company Thailand and Nephrology unit, Faculty of Medicine, Chulalongorn University to reduce gut-derived uremic toxin.<\/li>
        • The assay for Neutrophil extracellular traps (NETs) measuring CIT-H3 with a collaboration with National Science and Technology Development Agency : NSTDA.<\/li>
        • The plasma flux therapy \u2013 an initial machine is successfully built but the indication for using this machine needs more study.<\/li><\/ul><\/li><\/ul>
          1. High rank scientific research and network collaboration<\/li>
          2. Enhanced career development and increased funding from out-sources. The increased opportunity of the short-term visit for student will be beneficial for Thai Scientific community .<\/li><\/ol>
            1. \u00a0<\/li><\/ol>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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              Research Highlights<\/h3>\t\t<\/div>\n\t\t\n\t\t\t\t
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              1. Amornphimoltham P, Yuen PST, Star RA, Leelahavanichkul A. Gut Leakage of Fungal-Derived Inflammatory Mediators: Part of a Gut-Liver-Kidney Axis in Bacterial Sepsis. Dig Dis Sci. 2019 Sep;64(9):2416-2428. (impacts of leaky gut and fungi in the gut contents).<\/li>
              2. Chancharoenthana W, Kamolratanakul S, Schultz MJ, Leelahavanichkul A. The leaky gut and the gut microbiome in sepsis - targets in research and treatment. Clin Sci (Lond). 2023 Apr 26;137(8):645-662. (expertise in microbiome analysis and probiotics)<\/li>
              3. Charoensappakit A, Sae-Khow K, Rattanaliam P, Vutthikraivit N, Pecheenbuvan M, Udomkarnjananun S, Leelahavanichkul A. Cell-free DNA as diagnostic and prognostic biomarkers for adult sepsis: a systematic review and meta-analysis. Sci Rep. 2023 Nov 10;13(1):19624. (expertise in sepsis)<\/li><\/ol>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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                Networks and Partnerships<\/h3>\t\t<\/div>\n\t\t\n\t\t\t\t
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                • National Science and Technology Development Agency<\/span>\u00a0(NSTDA)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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                  • Faculty of Tropical Medicine Mahidol University<\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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                    • Department of Pharmacology at University of California San Diego School of Medicine; US.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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                      • The University of Queensland; Australia.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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                        • National Institute of Advanced Industrial Science and Technology (AIST); Japan.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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                          • Functional Cellular Networks Section<\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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                            • National Institute of Allergy and Infectious Diseases National Institutes of Health; US.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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                              Contact<\/h2>\t\t<\/div>\n\t\t\n\t\t\t\t
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                              Associate Professor, MD.,Ph.D.<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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                              Asadha Leewanichkul<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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                              Director of Research projects<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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                              Faculty of Medicine<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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                              \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t17th floor, Aor Por Ror building, Faculty of Medicine, Chulalongkorn University, Wangmai, Pathumwan Bangkok 10330\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

                              Center of Excellence in Translational Research in Inflammation and Immunology, The translation of the basic research into clinical practice; bench to bedside translation. Research & Innovation Focus \u200b Health and Well-Being + Health Health and Well-Being + BCG Health and Well-Being + Industry 4.0 Strategic Objectives Translation of basic knowledge in the control of inflammation and immune responses into the clinical situation (clinical practice or health advice) Discovery of the new knowledge for the control of inflammation and immune responses using translational research Target in 3 Years The innovation Probiotics-derived from Thai population (Lacticaseibacillus rhamnosus L34) is developing with Greater Pharma company Thailand and Nephrology unit, Faculty of Medicine, Chulalongorn University to reduce gut-derived uremic toxin. The assay for Neutrophil extracellular traps (NETs) measuring CIT-H3 with a collaboration with National Science and Technology Development Agency : NSTDA. The plasma flux therapy \u2013 an initial machine is successfully built but the indication for using this machine needs more study. High rank scientific research and network collaboration Enhanced career development and increased funding from out-sources. The increased opportunity of the short-term visit for student will be beneficial for Thai Scientific community . \u00a0 Research Highlights Amornphimoltham P, Yuen PST, Star RA, Leelahavanichkul A. Gut Leakage of Fungal-Derived Inflammatory Mediators: Part of a Gut-Liver-Kidney Axis in Bacterial Sepsis. Dig Dis Sci. 2019 Sep;64(9):2416-2428. (impacts of leaky gut and fungi in the gut contents). Chancharoenthana W, Kamolratanakul S, Schultz MJ, Leelahavanichkul A. The leaky gut and the gut microbiome in sepsis – targets in research and treatment. Clin Sci (Lond). 2023 Apr 26;137(8):645-662. (expertise in microbiome analysis and probiotics) Charoensappakit A, Sae-Khow K, Rattanaliam P, Vutthikraivit N, Pecheenbuvan M, Udomkarnjananun S, Leelahavanichkul A. Cell-free DNA as diagnostic and prognostic biomarkers for adult sepsis: a systematic review and meta-analysis. Sci Rep. 2023 Nov 10;13(1):19624. (expertise in sepsis) Networks and Partnerships National Science and Technology Development Agency\u00a0(NSTDA) Faculty of Tropical Medicine Mahidol University Department of Pharmacology at University of California San Diego School of Medicine; US. The University of Queensland; Australia. National Institute of Advanced Industrial Science and Technology (AIST); Japan. Functional Cellular Networks Section National Institute of Allergy and Infectious Diseases National Institutes of Health; US. Contact Associate Professor, MD.,Ph.D. Asadha Leewanichkul Director of Research projects Faculty of Medicine Affiliation 17th floor, Aor Por Ror building, Faculty of Medicine, Chulalongkorn University, Wangmai, Pathumwan Bangkok 10330<\/p>\n","protected":false},"author":4,"featured_media":11520,"parent":0,"menu_order":64,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_eb_attr":"","footnotes":""},"class_list":["post-11555","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nCenter of Excellence in Translational Research in Inflammation and Immunology - Research Chula<\/title>\n<meta name=\"description\" content=\"Translation of basic knowledge in the control of inflammation and immune responses into the clinical situation (clinical practice or health advice) Discovery of the new knowledge for the control of inflammation and immune responses using translational research\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.research.chula.ac.th\/en\/ce-translational-research-in-inflammation-and-immunology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Center of Excellence in Translational Research in Inflammation and Immunology - 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